Phosphorus in PDB 1agn: X-Ray Structure of Human Sigma Alcohol Dehydrogenase

Enzymatic activity of X-Ray Structure of Human Sigma Alcohol Dehydrogenase

All present enzymatic activity of X-Ray Structure of Human Sigma Alcohol Dehydrogenase:
1.1.1.1;

Protein crystallography data

The structure of X-Ray Structure of Human Sigma Alcohol Dehydrogenase, PDB code: 1agn was solved by T.D.Hurley, P.Xie, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 8.00 / 3.00
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 86.300, 94.650, 121.660, 90.00, 100.03, 90.00
R / Rfree (%) 22.5 / 30.5

Phosphorus Binding Sites:

The binding sites of Phosphorus atom in the X-Ray Structure of Human Sigma Alcohol Dehydrogenase (pdb code 1agn). This binding sites where shown within 5.0 Angstroms radius around Phosphorus atom.
In total 8 binding sites of Phosphorus where determined in the X-Ray Structure of Human Sigma Alcohol Dehydrogenase, PDB code: 1agn:
Jump to Phosphorus binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Phosphorus binding site 1 out of 8 in 1agn

Go back to Phosphorus Binding Sites List in 1agn
Phosphorus binding site 1 out of 8 in the X-Ray Structure of Human Sigma Alcohol Dehydrogenase


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 1 of X-Ray Structure of Human Sigma Alcohol Dehydrogenase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:P377

b:19.6
occ:1.00
PA A:NAD377 0.0 19.6 1.0
O1A A:NAD377 1.5 19.6 1.0
O2A A:NAD377 1.5 19.6 1.0
O3 A:NAD377 1.6 19.6 1.0
O5B A:NAD377 1.6 19.6 1.0
C5B A:NAD377 2.6 19.6 1.0
PN A:NAD377 2.9 19.6 1.0
O2N A:NAD377 3.4 19.6 1.0
CA A:GLY201 3.8 19.6 1.0
O1N A:NAD377 3.8 19.6 1.0
C4B A:NAD377 3.8 19.6 1.0
O5D A:NAD377 3.9 19.6 1.0
NE A:ARG47 4.2 19.6 1.0
C5D A:NAD377 4.2 19.6 1.0
N A:GLY202 4.2 19.6 1.0
CB A:ARG47 4.2 19.6 1.0
C3B A:NAD377 4.3 19.6 1.0
C A:GLY201 4.6 19.6 1.0
CG A:ARG47 4.7 19.6 1.0
NH2 A:ARG47 4.7 19.6 1.0
N A:GLY201 4.8 19.6 1.0
CZ A:ARG47 4.9 19.6 1.0
NH1 A:ARG369 4.9 19.6 1.0
O4B A:NAD377 5.0 19.6 1.0

Phosphorus binding site 2 out of 8 in 1agn

Go back to Phosphorus Binding Sites List in 1agn
Phosphorus binding site 2 out of 8 in the X-Ray Structure of Human Sigma Alcohol Dehydrogenase


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 2 of X-Ray Structure of Human Sigma Alcohol Dehydrogenase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:P377

b:19.6
occ:1.00
PN A:NAD377 0.0 19.6 1.0
O1N A:NAD377 1.5 19.6 1.0
O2N A:NAD377 1.5 19.6 1.0
O3 A:NAD377 1.5 19.6 1.0
O5D A:NAD377 1.6 19.6 1.0
C5D A:NAD377 2.7 19.6 1.0
PA A:NAD377 2.9 19.6 1.0
CB A:ARG47 3.4 19.6 1.0
O2A A:NAD377 3.5 19.6 1.0
O5B A:NAD377 3.7 19.6 1.0
O1A A:NAD377 3.9 19.6 1.0
CG2 A:VAL203 4.0 19.6 1.0
C4D A:NAD377 4.0 19.6 1.0
NH1 A:ARG369 4.0 19.6 1.0
N A:ARG47 4.2 19.6 1.0
O4D A:NAD377 4.2 19.6 1.0
N A:VAL203 4.3 19.6 1.0
NH2 A:ARG369 4.4 19.6 1.0
CB A:VAL203 4.4 19.6 1.0
N A:GLY202 4.4 19.6 1.0
CG A:ARG47 4.4 19.6 1.0
CA A:ARG47 4.5 19.6 1.0
C5B A:NAD377 4.6 19.6 1.0
C6N A:NAD377 4.7 19.6 1.0
CZ A:ARG369 4.7 19.6 1.0
C2D A:NAD377 4.7 19.6 1.0
C3D A:NAD377 4.8 19.6 1.0
SG A:CYS46 4.9 19.6 1.0
CA A:GLY201 5.0 19.6 1.0

Phosphorus binding site 3 out of 8 in 1agn

Go back to Phosphorus Binding Sites List in 1agn
Phosphorus binding site 3 out of 8 in the X-Ray Structure of Human Sigma Alcohol Dehydrogenase


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 3 of X-Ray Structure of Human Sigma Alcohol Dehydrogenase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:P377

b:15.4
occ:1.00
PA B:NAD377 0.0 15.4 1.0
O2A B:NAD377 1.5 15.4 1.0
O1A B:NAD377 1.5 15.4 1.0
O5B B:NAD377 1.5 15.4 1.0
O3 B:NAD377 1.6 15.4 1.0
C5B B:NAD377 2.5 15.4 1.0
PN B:NAD377 2.8 15.4 1.0
O5D B:NAD377 3.1 15.4 1.0
O2N B:NAD377 3.4 15.4 1.0
C4B B:NAD377 3.5 15.4 1.0
O1N B:NAD377 4.0 15.4 1.0
C3B B:NAD377 4.0 15.4 1.0
CA B:GLY201 4.0 15.4 1.0
CB B:ARG47 4.1 15.4 1.0
C5D B:NAD377 4.1 15.4 1.0
NE B:ARG47 4.3 15.4 1.0
CG B:ARG47 4.4 15.4 1.0
CD1 B:LEU362 4.5 15.4 1.0
N B:GLY202 4.7 15.4 1.0
O4B B:NAD377 4.8 15.4 1.0
N B:GLY201 4.8 15.4 1.0
C B:GLY201 4.9 15.4 1.0
NH2 B:ARG47 5.0 15.4 1.0
CD B:ARG47 5.0 15.4 1.0
O3B B:NAD377 5.0 15.4 1.0

Phosphorus binding site 4 out of 8 in 1agn

Go back to Phosphorus Binding Sites List in 1agn
Phosphorus binding site 4 out of 8 in the X-Ray Structure of Human Sigma Alcohol Dehydrogenase


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 4 of X-Ray Structure of Human Sigma Alcohol Dehydrogenase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:P377

b:15.4
occ:1.00
PN B:NAD377 0.0 15.4 1.0
O1N B:NAD377 1.5 15.4 1.0
O2N B:NAD377 1.5 15.4 1.0
O3 B:NAD377 1.5 15.4 1.0
O5D B:NAD377 1.6 15.4 1.0
C5D B:NAD377 2.7 15.4 1.0
PA B:NAD377 2.8 15.4 1.0
O5B B:NAD377 3.3 15.4 1.0
CB B:ARG47 3.7 15.4 1.0
C4D B:NAD377 3.7 15.4 1.0
O4D B:NAD377 3.7 15.4 1.0
O1A B:NAD377 3.7 15.4 1.0
O2A B:NAD377 3.8 15.4 1.0
CG2 B:VAL203 4.0 15.4 1.0
C3D B:NAD377 4.1 15.4 1.0
NH1 B:ARG369 4.2 15.4 1.0
N B:VAL203 4.3 15.4 1.0
CB B:VAL203 4.4 15.4 1.0
N B:GLY202 4.4 15.4 1.0
C2D B:NAD377 4.5 15.4 1.0
N B:ARG47 4.5 15.4 1.0
C5B B:NAD377 4.5 15.4 1.0
CG B:ARG47 4.6 15.4 1.0
CA B:ARG47 4.7 15.4 1.0
C1D B:NAD377 4.8 15.4 1.0
O B:VAL268 4.9 15.4 1.0
CA B:GLY201 4.9 15.4 1.0
CA B:VAL203 5.0 15.4 1.0

Phosphorus binding site 5 out of 8 in 1agn

Go back to Phosphorus Binding Sites List in 1agn
Phosphorus binding site 5 out of 8 in the X-Ray Structure of Human Sigma Alcohol Dehydrogenase


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 5 of X-Ray Structure of Human Sigma Alcohol Dehydrogenase within 5.0Å range:
probe atom residue distance (Å) B Occ
C:P377

b:25.9
occ:1.00
PA C:NAD377 0.0 25.9 1.0
O2A C:NAD377 1.5 25.9 1.0
O1A C:NAD377 1.5 25.9 1.0
O3 C:NAD377 1.5 25.9 1.0
O5B C:NAD377 1.6 25.9 1.0
C5B C:NAD377 2.6 25.9 1.0
PN C:NAD377 2.7 25.9 1.0
O2N C:NAD377 3.2 25.9 1.0
C4B C:NAD377 3.7 25.9 1.0
O1N C:NAD377 3.8 25.9 1.0
O5D C:NAD377 3.8 25.9 1.0
C5D C:NAD377 3.9 25.9 1.0
CB C:ARG47 3.9 25.9 1.0
NE C:ARG47 4.0 25.9 1.0
CA C:GLY201 4.0 25.9 1.0
N C:GLY202 4.2 25.9 1.0
CG C:ARG47 4.4 25.9 1.0
NH2 C:ARG47 4.4 25.9 1.0
C3B C:NAD377 4.5 25.9 1.0
C C:GLY201 4.6 25.9 1.0
CZ C:ARG47 4.7 25.9 1.0
CD C:ARG47 4.8 25.9 1.0
O4B C:NAD377 4.8 25.9 1.0
N C:GLY201 4.9 25.9 1.0

Phosphorus binding site 6 out of 8 in 1agn

Go back to Phosphorus Binding Sites List in 1agn
Phosphorus binding site 6 out of 8 in the X-Ray Structure of Human Sigma Alcohol Dehydrogenase


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 6 of X-Ray Structure of Human Sigma Alcohol Dehydrogenase within 5.0Å range:
probe atom residue distance (Å) B Occ
C:P377

b:25.9
occ:1.00
PN C:NAD377 0.0 25.9 1.0
O1N C:NAD377 1.5 25.9 1.0
O2N C:NAD377 1.5 25.9 1.0
O3 C:NAD377 1.6 25.9 1.0
O5D C:NAD377 1.6 25.9 1.0
C5D C:NAD377 2.6 25.9 1.0
PA C:NAD377 2.7 25.9 1.0
O2A C:NAD377 3.1 25.9 1.0
O5B C:NAD377 3.5 25.9 1.0
CB C:ARG47 3.8 25.9 1.0
CG2 C:VAL203 3.8 25.9 1.0
C4D C:NAD377 3.9 25.9 1.0
O1A C:NAD377 4.0 25.9 1.0
N C:VAL203 4.0 25.9 1.0
O4D C:NAD377 4.2 25.9 1.0
N C:GLY202 4.2 25.9 1.0
CB C:VAL203 4.2 25.9 1.0
NH1 C:ARG369 4.3 25.9 1.0
C2D C:NAD377 4.4 25.9 1.0
C3D C:NAD377 4.6 25.9 1.0
N C:ARG47 4.6 25.9 1.0
CG C:ARG47 4.6 25.9 1.0
CA C:GLY202 4.7 25.9 1.0
CA C:VAL203 4.8 25.9 1.0
C6N C:NAD377 4.8 25.9 1.0
CA C:ARG47 4.8 25.9 1.0
C C:GLY202 4.9 25.9 1.0
C C:GLY201 4.9 25.9 1.0
C5B C:NAD377 4.9 25.9 1.0
NH2 C:ARG369 5.0 25.9 1.0
C1D C:NAD377 5.0 25.9 1.0

Phosphorus binding site 7 out of 8 in 1agn

Go back to Phosphorus Binding Sites List in 1agn
Phosphorus binding site 7 out of 8 in the X-Ray Structure of Human Sigma Alcohol Dehydrogenase


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 7 of X-Ray Structure of Human Sigma Alcohol Dehydrogenase within 5.0Å range:
probe atom residue distance (Å) B Occ
D:P377

b:14.9
occ:1.00
PA D:NAD377 0.0 14.9 1.0
O2A D:NAD377 1.5 14.9 1.0
O1A D:NAD377 1.5 14.9 1.0
O5B D:NAD377 1.6 14.9 1.0
O3 D:NAD377 1.6 14.9 1.0
C5B D:NAD377 2.8 14.9 1.0
PN D:NAD377 2.9 14.9 1.0
O5D D:NAD377 3.6 14.9 1.0
O2N D:NAD377 3.6 14.9 1.0
C4B D:NAD377 3.8 14.9 1.0
O1N D:NAD377 4.1 14.9 1.0
CA D:GLY201 4.1 14.9 1.0
C3B D:NAD377 4.1 14.9 1.0
NE D:ARG47 4.1 14.9 1.0
CB D:ARG47 4.3 14.9 1.0
CD1 D:LEU362 4.4 14.9 1.0
N D:GLY202 4.4 14.9 1.0
NH2 D:ARG47 4.5 14.9 1.0
CG D:ARG47 4.8 14.9 1.0
CZ D:ARG47 4.8 14.9 1.0
C D:GLY201 4.8 14.9 1.0
C5D D:NAD377 4.9 14.9 1.0

Phosphorus binding site 8 out of 8 in 1agn

Go back to Phosphorus Binding Sites List in 1agn
Phosphorus binding site 8 out of 8 in the X-Ray Structure of Human Sigma Alcohol Dehydrogenase


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 8 of X-Ray Structure of Human Sigma Alcohol Dehydrogenase within 5.0Å range:
probe atom residue distance (Å) B Occ
D:P377

b:14.9
occ:1.00
PN D:NAD377 0.0 14.9 1.0
O1N D:NAD377 1.5 14.9 1.0
O2N D:NAD377 1.5 14.9 1.0
O5D D:NAD377 1.6 14.9 1.0
O3 D:NAD377 1.6 14.9 1.0
C5D D:NAD377 2.5 14.9 1.0
PA D:NAD377 2.9 14.9 1.0
O5B D:NAD377 3.2 14.9 1.0
CB D:ARG47 3.7 14.9 1.0
CG2 D:VAL203 3.8 14.9 1.0
O2A D:NAD377 3.8 14.9 1.0
C4D D:NAD377 3.8 14.9 1.0
O1A D:NAD377 4.0 14.9 1.0
N D:GLY202 4.1 14.9 1.0
N D:VAL203 4.2 14.9 1.0
NH1 D:ARG369 4.3 14.9 1.0
N D:ARG47 4.3 14.9 1.0
C5B D:NAD377 4.4 14.9 1.0
NH2 D:ARG369 4.5 14.9 1.0
CB D:VAL203 4.5 14.9 1.0
C3D D:NAD377 4.6 14.9 1.0
CA D:ARG47 4.7 14.9 1.0
CG D:ARG47 4.7 14.9 1.0
CZ D:ARG369 4.7 14.9 1.0
CA D:GLY202 4.7 14.9 1.0
O4D D:NAD377 4.8 14.9 1.0
CA D:GLY201 4.9 14.9 1.0
C D:GLY201 4.9 14.9 1.0
CA D:VAL203 5.0 14.9 1.0

Reference:

P.Xie, S.H.Parsons, D.C.Speckhard, W.F.Bosron, T.D.Hurley. X-Ray Structure of Human Class IV Sigmasigma Alcohol Dehydrogenase. Structural Basis For Substrate Specificity. J.Biol.Chem. V. 272 18558 1997.
ISSN: ISSN 0021-9258
PubMed: 9228021
DOI: 10.1074/JBC.272.30.18558
Page generated: Fri Sep 25 12:52:33 2020

Last articles

Zn in 7M6U
Zn in 7NNG
Zn in 7NEE
Zn in 7NEU
Zn in 7M3K
Zn in 7KWD
Zn in 7KYH
Zn in 7KNG
Zn in 7KY2
Zn in 7KYF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy