Phosphorus in PDB 1ado: Fructose 1,6-Bisphosphate Aldolase From Rabbit Muscle

All present enzymatic activity of Fructose 1,6-Bisphosphate Aldolase From Rabbit Muscle:
4.1.2.13;

The structure of Fructose 1,6-Bisphosphate Aldolase From Rabbit Muscle, PDB code: 1ado was solved by N.S.Blom, J.Sygusch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	12.00 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	163.880, 57.470, 85.030, 90.00, 102.70, 90.00
R / Rfree (%)	16.2 / 20.3

The binding sites of Phosphorus atom in the Fructose 1,6-Bisphosphate Aldolase From Rabbit Muscle (pdb code 1ado). This binding sites where shown within 5.0 Angstroms radius around Phosphorus atom.
In total 3 binding sites of Phosphorus where determined in the Fructose 1,6-Bisphosphate Aldolase From Rabbit Muscle, PDB code: 1ado:
Jump to Phosphorus binding site number: 1; 2; 3;

Phosphorus binding site 1 out of 3 in the Fructose 1,6-Bisphosphate Aldolase From Rabbit Muscle


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 1 of Fructose 1,6-Bisphosphate Aldolase From Rabbit Muscle within 5.0Å range: probe atom residue distance (Å) B Occ A:P1104 b:57.9 occ:0.50 P A:13P1104 0.0 57.9 0.5 P A:13P1104 0.3 54.8 0.5 O3P A:13P1104 1.4 52.4 0.5 O1P A:13P1104 1.5 55.1 0.5 O3P A:13P1104 1.6 56.8 0.5 O2P A:13P1104 1.6 55.2 0.5 O1P A:13P1104 1.6 56.0 0.5 O1 A:13P1104 1.6 55.7 0.5 O1 A:13P1104 1.8 50.4 0.5 O2P A:13P1104 1.8 52.6 0.5 HOP2 A:13P1104 2.1 56.1 0.5 HOP2 A:13P1104 2.3 53.9 0.5 H A:GLY302 2.6 14.3 1.0 C1 A:13P1104 2.7 51.5 0.5 C1 A:13P1104 2.7 45.1 0.5 H A:SER271 3.0 17.8 1.0 N A:GLY302 3.4 14.0 1.0 HG A:SER271 3.6 24.5 1.0 H A:GLY272 3.6 25.1 1.0 C2 A:13P1104 3.7 50.5 0.5 OG A:SER271 3.8 28.6 1.0 HZ3 A:LYS229 3.8 9.2 1.0 N A:SER271 3.9 18.5 1.0 H A:ARG303 3.9 21.0 1.0 O A:SER300 4.0 14.1 1.0 C2 A:13P1104 4.0 41.7 0.5 CA A:GLY302 4.1 15.0 1.0 O A:HOH1333 4.1 34.1 1.0 HO3 A:13P1104 4.1 47.3 0.5 O2 A:13P1104 4.1 51.0 0.5 CB A:LEU270 4.2 15.3 1.0 C A:TYR301 4.3 13.4 1.0 CA A:LEU270 4.3 16.3 1.0 CA A:TYR301 4.4 12.0 1.0 C3 A:13P1104 4.4 40.6 0.5 O A:HOH1579 4.5 42.2 1.0 O3 A:13P1104 4.5 47.9 0.5 N A:GLY272 4.6 24.8 1.0 C A:LEU270 4.6 17.3 1.0 N A:ARG303 4.8 20.4 1.0 C3 A:13P1104 4.8 49.0 0.5 CA A:SER271 4.8 23.0 1.0 NZ A:LYS229 4.8 10.0 1.0 CB A:SER271 4.8 23.7 1.0 C A:SER300 5.0 12.6 1.0 C A:GLY302 5.0 15.2 1.0 CE A:LYS229 5.0 9.4 1.0

Phosphorus binding site 2 out of 3 in the Fructose 1,6-Bisphosphate Aldolase From Rabbit Muscle


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 2 of Fructose 1,6-Bisphosphate Aldolase From Rabbit Muscle within 5.0Å range: probe atom residue distance (Å) B Occ A:P1104 b:54.8 occ:0.50 P A:13P1104 0.0 54.8 0.5 P A:13P1104 0.3 57.9 0.5 O3P A:13P1104 1.4 56.8 0.5 O3P A:13P1104 1.6 52.4 0.5 O1P A:13P1104 1.6 56.0 0.5 O2P A:13P1104 1.6 52.6 0.5 O1P A:13P1104 1.6 55.1 0.5 O1 A:13P1104 1.6 50.4 0.5 O2P A:13P1104 1.8 55.2 0.5 O1 A:13P1104 1.8 55.7 0.5 HOP2 A:13P1104 2.1 53.9 0.5 HOP2 A:13P1104 2.2 56.1 0.5 C1 A:13P1104 2.7 45.1 0.5 C1 A:13P1104 2.8 51.5 0.5 H A:GLY302 2.9 14.3 1.0 H A:SER271 3.2 17.8 1.0 H A:GLY272 3.6 25.1 1.0 N A:GLY302 3.7 14.0 1.0 C2 A:13P1104 3.7 50.5 0.5 HG A:SER271 3.8 24.5 1.0 HZ3 A:LYS229 3.8 9.2 1.0 O A:HOH1333 3.8 34.1 1.0 C2 A:13P1104 3.9 41.7 0.5 OG A:SER271 4.0 28.6 1.0 HO3 A:13P1104 4.0 47.3 0.5 N A:SER271 4.0 18.5 1.0 CB A:LEU270 4.1 15.3 1.0 O A:SER300 4.1 14.1 1.0 H A:ARG303 4.1 21.0 1.0 C3 A:13P1104 4.2 40.6 0.5 O2 A:13P1104 4.2 51.0 0.5 CA A:GLY302 4.3 15.0 1.0 CA A:LEU270 4.3 16.3 1.0 O A:HOH1579 4.4 42.2 1.0 O3 A:13P1104 4.5 47.9 0.5 C A:TYR301 4.5 13.4 1.0 N A:GLY272 4.6 24.8 1.0 CA A:TYR301 4.6 12.0 1.0 C A:LEU270 4.6 17.3 1.0 NZ A:LYS229 4.7 10.0 1.0 C3 A:13P1104 4.8 49.0 0.5 CE A:LYS229 4.9 9.4 1.0 O3 A:13P1104 4.9 38.1 0.5 HO3 A:13P1104 4.9 39.5 0.5 CA A:SER271 4.9 23.0 1.0 O2 A:13P1104 5.0 38.5 0.5 N A:ARG303 5.0 20.4 1.0

Phosphorus binding site 3 out of 3 in the Fructose 1,6-Bisphosphate Aldolase From Rabbit Muscle


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 3 of Fructose 1,6-Bisphosphate Aldolase From Rabbit Muscle within 5.0Å range: probe atom residue distance (Å) B Occ B:P1053 b:41.6 occ:0.70 P B:13P1053 0.0 41.6 0.7 O3P B:13P1053 1.6 42.1 0.7 O2P B:13P1053 1.6 40.2 0.7 O1P B:13P1053 1.6 41.0 0.7 O1 B:13P1053 1.6 40.8 0.7 HOP2 B:13P1053 2.1 40.6 0.7 C1 B:13P1053 2.6 39.2 0.7 H B:GLY302 2.9 16.0 1.0 H B:SER271 3.0 18.2 1.0 H B:GLY272 3.2 23.7 1.0 O B:HOH1155 3.3 34.1 1.0 OG B:SER271 3.4 25.1 1.0 H B:ARG303 3.4 21.9 1.0 C2 B:13P1053 3.5 41.8 0.7 C3 B:13P1053 3.7 43.4 0.7 HG B:SER271 3.7 23.6 1.0 N B:SER271 3.8 19.2 1.0 N B:GLY302 3.8 15.4 1.0 O B:HOH1198 3.9 24.8 1.0 N B:GLY272 4.0 23.5 1.0 CA B:GLY302 4.2 17.1 1.0 N B:ARG303 4.3 21.8 1.0 CB B:LEU270 4.4 13.8 1.0 CB B:SER271 4.5 22.4 1.0 CA B:SER271 4.5 21.8 1.0 H B:GLY273 4.5 23.4 1.0 O2 B:13P1053 4.5 41.9 0.7 C B:LEU270 4.6 15.4 1.0 CA B:LEU270 4.7 15.4 1.0 O B:HOH1533 4.7 32.3 1.0 H B:ALA304 4.7 23.7 1.0 C B:SER271 4.8 23.9 1.0 C B:GLY302 4.8 17.6 1.0 C B:TYR301 4.8 11.7 1.0 O B:SER300 4.9 10.3 1.0 CA B:GLY272 4.9 24.4 1.0 O3 B:13P1053 5.0 43.9 0.7

N.Blom, J.Sygusch. Product Binding and Role of the C-Terminal Region in Class I D-Fructose 1,6-Bisphosphate Aldolase. Nat.Struct.Biol. V. 4 36 1997.
ISSN: ISSN 1072-8368
PubMed: 8989320
DOI: 10.1038/NSB0197-36