Phosphorus in PDB 1adc: Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes

Enzymatic activity of Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes

All present enzymatic activity of Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes:
1.1.1.1;

Protein crystallography data

The structure of Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes, PDB code: 1adc was solved by H.Li, W.A.Hallows, J.S.Punzi, K.W.Pankiewicz, K.A.Watanabe, B.M.Goldstein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) N/A / 2.70
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 51.900, 44.800, 93.000, 103.10, 87.80, 70.40
R / Rfree (%) 17 / n/a

Phosphorus Binding Sites:

The binding sites of Phosphorus atom in the Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes (pdb code 1adc). This binding sites where shown within 5.0 Angstroms radius around Phosphorus atom.
In total 4 binding sites of Phosphorus where determined in the Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes, PDB code: 1adc:
Jump to Phosphorus binding site number: 1; 2; 3; 4;

Phosphorus binding site 1 out of 4 in 1adc

Go back to Phosphorus Binding Sites List in 1adc
Phosphorus binding site 1 out of 4 in the Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 1 of Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes within 5.0Å range:
probe atom residue distance (Å) B Occ
A:P377

b:10.2
occ:1.00
 PA A:PAD377 0.0 10.2 1.0
O2A A:PAD377 1.5 11.9 1.0
O1A A:PAD377 1.5 2.0 1.0
O3 A:PAD377 1.6 2.0 1.0
O5B A:PAD377 1.6 21.0 1.0
C5B A:PAD377 2.7 18.8 1.0
PN A:PAD377 2.8 10.3 1.0
O2N A:PAD377 3.2 13.4 1.0
HH11 A:ARG47 3.3 15.0 1.0
O1N A:PAD377 3.7 14.9 1.0
CD A:ARG47 3.8 2.0 1.0
C4B A:PAD377 3.9 11.9 1.0
H A:GLY202 4.0 15.0 1.0
O5D A:PAD377 4.0 15.7 1.0
C3B A:PAD377 4.1 8.9 1.0
CA A:GLY201 4.2 3.8 1.0
NH1 A:ARG47 4.3 10.8 1.0
CB A:ARG47 4.3 2.0 1.0
C5D A:PAD377 4.4 8.7 1.0
CG A:ARG47 4.5 2.0 1.0
HH12 A:ARG369 4.7 15.0 1.0
N A:GLY202 4.8 3.8 1.0
H A:GLY201 4.8 15.0 1.0
O3B A:PAD377 4.8 12.1 1.0
NE A:ARG47 4.9 2.0 1.0
HH12 A:ARG47 4.9 15.0 1.0
N A:GLY201 4.9 10.3 1.0
C A:GLY201 5.0 5.7 1.0

Phosphorus binding site 2 out of 4 in 1adc

Go back to Phosphorus Binding Sites List in 1adc
Phosphorus binding site 2 out of 4 in the Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 2 of Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes within 5.0Å range:
probe atom residue distance (Å) B Occ
A:P377

b:10.3
occ:1.00
 PN A:PAD377 0.0 10.3 1.0
O1N A:PAD377 1.5 14.9 1.0
O2N A:PAD377 1.5 13.4 1.0
O3 A:PAD377 1.6 2.0 1.0
O5D A:PAD377 1.6 15.7 1.0
C5D A:PAD377 2.7 8.7 1.0
PA A:PAD377 2.8 10.2 1.0
O2A A:PAD377 3.1 11.9 1.0
O5B A:PAD377 3.2 21.0 1.0
H A:VAL203 3.4 15.0 1.0
HH12 A:ARG369 3.5 15.0 1.0
H A:ARG47 3.5 15.0 1.0
CB A:ARG47 3.6 2.0 1.0
CG2 A:VAL203 3.6 14.4 1.0
C4D A:PAD377 3.9 4.8 1.0
H A:GLY202 4.0 15.0 1.0
HH22 A:ARG369 4.1 15.0 1.0
O1A A:PAD377 4.1 2.0 1.0
C3D A:PAD377 4.2 4.2 1.0
N A:VAL203 4.3 11.0 1.0
C5B A:PAD377 4.3 18.8 1.0
N A:ARG47 4.4 6.3 1.0
CB A:VAL203 4.4 11.5 1.0
N A:GLY202 4.5 3.8 1.0
NH1 A:ARG369 4.5 2.5 1.0
CG A:ARG47 4.5 2.0 1.0
O4D A:PAD377 4.6 2.0 1.0
CA A:ARG47 4.6 3.0 1.0
CD A:ARG47 4.7 2.0 1.0
C2D A:PAD377 4.7 3.2 1.0
H A:GLY204 4.8 15.0 1.0
NH2 A:ARG369 4.9 4.4 1.0

Phosphorus binding site 3 out of 4 in 1adc

Go back to Phosphorus Binding Sites List in 1adc
Phosphorus binding site 3 out of 4 in the Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 3 of Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes within 5.0Å range:
probe atom residue distance (Å) B Occ
B:P377

b:16.3
occ:1.00
 PA B:PAD377 0.0 16.3 1.0
O1A B:PAD377 1.5 4.1 1.0
O2A B:PAD377 1.5 9.2 1.0
O5B B:PAD377 1.6 15.9 1.0
O3 B:PAD377 1.6 11.1 1.0
C5B B:PAD377 2.7 12.7 1.0
PN B:PAD377 3.0 10.6 1.0
HH11 B:ARG47 3.1 15.0 1.0
O2N B:PAD377 3.4 9.2 1.0
CD B:ARG47 3.7 2.0 1.0
O1N B:PAD377 3.8 16.2 1.0
C4B B:PAD377 3.9 10.5 1.0
O5D B:PAD377 4.0 13.2 1.0
NH1 B:ARG47 4.1 4.5 1.0
CB B:ARG47 4.2 9.8 1.0
H B:GLY202 4.2 15.0 1.0
CD2 B:LEU362 4.2 3.9 1.0
CG B:ARG47 4.2 6.9 1.0
C5D B:PAD377 4.2 8.3 1.0
CA B:GLY201 4.2 5.2 1.0
C3B B:PAD377 4.3 14.2 1.0
HH12 B:ARG47 4.6 15.0 1.0
HZ1 B:LYS228 4.7 15.0 1.0
NE B:ARG47 4.7 2.0 1.0
HH12 B:ARG369 4.8 15.0 1.0
CZ B:ARG47 4.9 2.0 1.0
HZ2 B:LYS228 4.9 15.0 1.0
H B:ARG47 4.9 15.0 1.0
N B:GLY202 5.0 2.0 1.0
O4B B:PAD377 5.0 8.9 1.0

Phosphorus binding site 4 out of 4 in 1adc

Go back to Phosphorus Binding Sites List in 1adc
Phosphorus binding site 4 out of 4 in the Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 4 of Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes within 5.0Å range:
probe atom residue distance (Å) B Occ
B:P377

b:10.6
occ:1.00
 PN B:PAD377 0.0 10.6 1.0
O2N B:PAD377 1.5 9.2 1.0
O1N B:PAD377 1.5 16.2 1.0
O3 B:PAD377 1.6 11.1 1.0
O5D B:PAD377 1.6 13.2 1.0
C5D B:PAD377 2.8 8.3 1.0
PA B:PAD377 3.0 16.3 1.0
HH12 B:ARG369 3.3 15.0 1.0
O2A B:PAD377 3.3 9.2 1.0
H B:ARG47 3.4 15.0 1.0
CG2 B:VAL203 3.5 16.9 1.0
H B:VAL203 3.5 15.0 1.0
CB B:ARG47 3.6 9.8 1.0
O5B B:PAD377 3.6 15.9 1.0
H B:GLY202 3.8 15.0 1.0
HH22 B:ARG369 4.0 15.0 1.0
O1A B:PAD377 4.1 4.1 1.0
C4D B:PAD377 4.1 3.5 1.0
NH1 B:ARG369 4.2 12.0 1.0
N B:ARG47 4.3 11.2 1.0
N B:GLY202 4.4 2.0 1.0
N B:VAL203 4.5 7.1 1.0
CG B:ARG47 4.5 6.9 1.0
CA B:ARG47 4.6 6.5 1.0
C3D B:PAD377 4.6 2.0 1.0
C5B B:PAD377 4.6 12.7 1.0
HH11 B:ARG369 4.7 15.0 1.0
CB B:VAL203 4.7 13.4 1.0
O4D B:PAD377 4.8 8.6 1.0
CG1 B:VAL203 4.8 18.5 1.0
NH2 B:ARG369 4.8 17.7 1.0
H B:GLY204 4.8 15.0 1.0
CA B:GLY201 4.8 5.2 1.0
CD B:ARG47 4.9 2.0 1.0
C2D B:PAD377 4.9 6.1 1.0
CZ B:ARG369 5.0 13.0 1.0

Reference:

H.Li, W.H.Hallows, J.S.Punzi, K.W.Pankiewicz, K.A.Watanabe, B.M.Goldstein. Crystallographic Studies of Isosteric Nad Analogues Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes. Biochemistry V. 33 11734 1994.
ISSN: ISSN 0006-2960
PubMed: 7918390
DOI: 10.1021/BI00205A009
Page generated: Fri Sep 25 12:45:42 2020

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy