Phosphorus in PDB 1a9c: Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
Enzymatic activity of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
All present enzymatic activity of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp:
3.5.4.16;
Protein crystallography data
The structure of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp, PDB code: 1a9c
was solved by
G.Auerbach,
H.Nar,
A.Bracher,
A.Bacher,
R.Huber,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
8.00 /
2.90
|
Space group
|
C 2 2 21 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
313.900,
226.800,
131.400,
90.00,
90.00,
90.00
|
R / Rfree (%)
|
20.6 /
28.8
|
Phosphorus Binding Sites:
Phosphorus binding site 1 out
of 45 in 1a9c
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Phosphorus Binding Sites List in 1a9c
Phosphorus binding site 1 out
of 45 in the Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
Mono view
Stereo pair view
|
A full contact list of Phosphorus with other atoms in the P binding
site number 1 of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:P401
b:20.9
occ:1.00
|
PG
|
A:GTP401
|
0.0
|
20.9
|
1.0
|
O1G
|
A:GTP401
|
1.5
|
18.7
|
1.0
|
O2G
|
A:GTP401
|
1.5
|
17.3
|
1.0
|
O3G
|
A:GTP401
|
1.6
|
14.1
|
1.0
|
O3B
|
A:GTP401
|
1.7
|
32.8
|
1.0
|
HH12
|
A:ARG185
|
2.6
|
20.0
|
0.0
|
HH11
|
B:ARG139
|
2.6
|
20.0
|
0.0
|
HH22
|
A:ARG185
|
2.8
|
20.0
|
0.0
|
PB
|
A:GTP401
|
2.9
|
28.1
|
1.0
|
HH12
|
B:ARG139
|
3.1
|
20.0
|
0.0
|
HZ2
|
B:LYS136
|
3.2
|
20.0
|
0.0
|
O1B
|
A:GTP401
|
3.2
|
35.3
|
1.0
|
NH1
|
B:ARG139
|
3.2
|
2.0
|
1.0
|
OG
|
B:SER135
|
3.5
|
22.0
|
1.0
|
NH1
|
A:ARG185
|
3.5
|
58.1
|
1.0
|
O2B
|
A:GTP401
|
3.6
|
16.5
|
1.0
|
NH2
|
A:ARG185
|
3.8
|
39.3
|
1.0
|
HG
|
B:SER135
|
3.8
|
20.0
|
0.0
|
HZ3
|
B:LYS136
|
4.0
|
20.0
|
0.0
|
NZ
|
B:LYS136
|
4.0
|
11.1
|
1.0
|
CZ
|
A:ARG185
|
4.1
|
27.8
|
1.0
|
O3A
|
A:GTP401
|
4.2
|
10.7
|
1.0
|
HH11
|
A:ARG185
|
4.2
|
20.0
|
0.0
|
HE2
|
A:HIS113
|
4.4
|
20.0
|
0.0
|
CB
|
B:SER135
|
4.4
|
3.4
|
1.0
|
C3'
|
A:GTP401
|
4.4
|
21.7
|
1.0
|
HH21
|
A:ARG185
|
4.6
|
20.0
|
0.0
|
CZ
|
B:ARG139
|
4.6
|
8.8
|
1.0
|
CE1
|
A:HIS113
|
4.7
|
34.6
|
1.0
|
CE
|
B:LYS136
|
4.7
|
7.8
|
1.0
|
O3'
|
A:GTP401
|
4.7
|
13.7
|
1.0
|
O1A
|
A:GTP401
|
4.8
|
28.0
|
1.0
|
HZ1
|
B:LYS136
|
4.8
|
20.0
|
0.0
|
O5'
|
A:GTP401
|
4.8
|
32.4
|
1.0
|
NE2
|
A:HIS113
|
4.9
|
19.0
|
1.0
|
PA
|
A:GTP401
|
5.0
|
29.9
|
1.0
|
H
|
A:ILE187
|
5.0
|
20.0
|
0.0
|
O2'
|
A:GTP401
|
5.0
|
36.6
|
1.0
|
|
Phosphorus binding site 2 out
of 45 in 1a9c
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Phosphorus Binding Sites List in 1a9c
Phosphorus binding site 2 out
of 45 in the Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
Mono view
Stereo pair view
|
A full contact list of Phosphorus with other atoms in the P binding
site number 2 of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:P401
b:28.1
occ:1.00
|
PB
|
A:GTP401
|
0.0
|
28.1
|
1.0
|
O1B
|
A:GTP401
|
1.5
|
35.3
|
1.0
|
O2B
|
A:GTP401
|
1.5
|
16.5
|
1.0
|
O3A
|
A:GTP401
|
1.6
|
10.7
|
1.0
|
O3B
|
A:GTP401
|
1.6
|
32.8
|
1.0
|
PA
|
A:GTP401
|
2.9
|
29.9
|
1.0
|
HE2
|
A:HIS113
|
2.9
|
20.0
|
0.0
|
PG
|
A:GTP401
|
2.9
|
20.9
|
1.0
|
HH22
|
A:ARG185
|
3.0
|
20.0
|
0.0
|
O1A
|
A:GTP401
|
3.1
|
28.0
|
1.0
|
O1G
|
A:GTP401
|
3.2
|
18.7
|
1.0
|
O5'
|
A:GTP401
|
3.6
|
32.4
|
1.0
|
NE2
|
A:HIS113
|
3.7
|
19.0
|
1.0
|
NH2
|
A:ARG185
|
3.7
|
39.3
|
1.0
|
HZ3
|
B:LYS136
|
3.8
|
20.0
|
0.0
|
O2G
|
A:GTP401
|
3.8
|
17.3
|
1.0
|
HH21
|
A:ARG185
|
3.9
|
20.0
|
0.0
|
O3G
|
A:GTP401
|
4.0
|
14.1
|
1.0
|
CE1
|
A:HIS113
|
4.1
|
34.6
|
1.0
|
O2A
|
A:GTP401
|
4.1
|
38.4
|
1.0
|
C5'
|
A:GTP401
|
4.2
|
17.4
|
1.0
|
HZ2
|
B:LYS136
|
4.2
|
20.0
|
0.0
|
HH12
|
A:ARG185
|
4.4
|
20.0
|
0.0
|
NZ
|
B:LYS136
|
4.5
|
11.1
|
1.0
|
CZ
|
A:ARG185
|
4.8
|
27.8
|
1.0
|
C3'
|
A:GTP401
|
4.9
|
21.7
|
1.0
|
CD2
|
A:HIS113
|
5.0
|
22.5
|
1.0
|
|
Phosphorus binding site 3 out
of 45 in 1a9c
Go back to
Phosphorus Binding Sites List in 1a9c
Phosphorus binding site 3 out
of 45 in the Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
Mono view
Stereo pair view
|
A full contact list of Phosphorus with other atoms in the P binding
site number 3 of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:P401
b:29.9
occ:1.00
|
PA
|
A:GTP401
|
0.0
|
29.9
|
1.0
|
O2A
|
A:GTP401
|
1.5
|
38.4
|
1.0
|
O1A
|
A:GTP401
|
1.5
|
28.0
|
1.0
|
O5'
|
A:GTP401
|
1.6
|
32.4
|
1.0
|
O3A
|
A:GTP401
|
1.6
|
10.7
|
1.0
|
C5'
|
A:GTP401
|
2.7
|
17.4
|
1.0
|
PB
|
A:GTP401
|
2.9
|
28.1
|
1.0
|
O1B
|
A:GTP401
|
3.2
|
35.3
|
1.0
|
HZ3
|
B:LYS136
|
3.5
|
20.0
|
0.0
|
O3B
|
A:GTP401
|
3.5
|
32.8
|
1.0
|
CG2
|
B:THR87
|
3.8
|
26.0
|
1.0
|
OG1
|
B:THR87
|
3.8
|
35.5
|
1.0
|
C4'
|
A:GTP401
|
3.8
|
19.0
|
1.0
|
HG1
|
B:THR87
|
3.9
|
20.0
|
0.0
|
O2B
|
A:GTP401
|
4.1
|
16.5
|
1.0
|
C3'
|
A:GTP401
|
4.3
|
21.7
|
1.0
|
CB
|
B:THR87
|
4.3
|
22.2
|
1.0
|
NZ
|
B:LYS136
|
4.4
|
11.1
|
1.0
|
CE
|
B:LYS136
|
4.6
|
7.8
|
1.0
|
HZ2
|
B:LYS136
|
4.7
|
20.0
|
0.0
|
HE2
|
A:HIS113
|
4.8
|
20.0
|
0.0
|
HD1
|
A:HIS112
|
4.9
|
20.0
|
0.0
|
PG
|
A:GTP401
|
5.0
|
20.9
|
1.0
|
O3'
|
A:GTP401
|
5.0
|
13.7
|
1.0
|
|
Phosphorus binding site 4 out
of 45 in 1a9c
Go back to
Phosphorus Binding Sites List in 1a9c
Phosphorus binding site 4 out
of 45 in the Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
Mono view
Stereo pair view
|
A full contact list of Phosphorus with other atoms in the P binding
site number 4 of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:P402
b:16.7
occ:1.00
|
PG
|
B:GTP402
|
0.0
|
16.7
|
1.0
|
O2G
|
B:GTP402
|
1.5
|
17.5
|
1.0
|
O1G
|
B:GTP402
|
1.5
|
12.2
|
1.0
|
O3G
|
B:GTP402
|
1.6
|
12.7
|
1.0
|
O3B
|
B:GTP402
|
1.7
|
26.1
|
1.0
|
HH11
|
C:ARG139
|
2.5
|
20.0
|
0.0
|
HH12
|
B:ARG185
|
2.7
|
20.0
|
0.0
|
HH12
|
C:ARG139
|
2.8
|
20.0
|
0.0
|
PB
|
B:GTP402
|
2.9
|
24.7
|
1.0
|
HH22
|
B:ARG185
|
3.0
|
20.0
|
0.0
|
HZ2
|
C:LYS136
|
3.0
|
20.0
|
0.0
|
NH1
|
C:ARG139
|
3.0
|
20.5
|
1.0
|
O1B
|
B:GTP402
|
3.1
|
34.1
|
1.0
|
OG
|
C:SER135
|
3.6
|
16.1
|
1.0
|
O2B
|
B:GTP402
|
3.6
|
32.7
|
1.0
|
NH1
|
B:ARG185
|
3.7
|
29.9
|
1.0
|
HG
|
C:SER135
|
3.8
|
20.0
|
0.0
|
NH2
|
B:ARG185
|
3.9
|
26.8
|
1.0
|
HZ3
|
C:LYS136
|
3.9
|
20.0
|
0.0
|
NZ
|
C:LYS136
|
3.9
|
17.9
|
1.0
|
O3A
|
B:GTP402
|
4.1
|
21.1
|
1.0
|
CZ
|
B:ARG185
|
4.2
|
13.4
|
1.0
|
CZ
|
C:ARG139
|
4.3
|
16.5
|
1.0
|
HH11
|
B:ARG185
|
4.3
|
20.0
|
0.0
|
HE2
|
B:HIS113
|
4.4
|
20.0
|
0.0
|
C3'
|
B:GTP402
|
4.4
|
17.7
|
1.0
|
CB
|
C:SER135
|
4.5
|
2.0
|
1.0
|
CE
|
C:LYS136
|
4.6
|
2.0
|
1.0
|
HH21
|
B:ARG185
|
4.7
|
20.0
|
0.0
|
HZ1
|
C:LYS136
|
4.7
|
20.0
|
0.0
|
O3'
|
B:GTP402
|
4.7
|
32.2
|
1.0
|
O1A
|
B:GTP402
|
4.7
|
20.8
|
1.0
|
O5'
|
B:GTP402
|
4.8
|
9.9
|
1.0
|
CE1
|
B:HIS113
|
4.8
|
20.3
|
1.0
|
CD
|
C:ARG139
|
4.9
|
17.0
|
1.0
|
H
|
B:ILE187
|
4.9
|
20.0
|
0.0
|
PA
|
B:GTP402
|
4.9
|
16.1
|
1.0
|
NE2
|
B:HIS113
|
4.9
|
3.4
|
1.0
|
|
Phosphorus binding site 5 out
of 45 in 1a9c
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Phosphorus Binding Sites List in 1a9c
Phosphorus binding site 5 out
of 45 in the Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
Mono view
Stereo pair view
|
A full contact list of Phosphorus with other atoms in the P binding
site number 5 of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:P402
b:24.7
occ:1.00
|
PB
|
B:GTP402
|
0.0
|
24.7
|
1.0
|
O1B
|
B:GTP402
|
1.5
|
34.1
|
1.0
|
O2B
|
B:GTP402
|
1.5
|
32.7
|
1.0
|
O3A
|
B:GTP402
|
1.6
|
21.1
|
1.0
|
O3B
|
B:GTP402
|
1.6
|
26.1
|
1.0
|
PG
|
B:GTP402
|
2.9
|
16.7
|
1.0
|
HE2
|
B:HIS113
|
2.9
|
20.0
|
0.0
|
PA
|
B:GTP402
|
2.9
|
16.1
|
1.0
|
HH22
|
B:ARG185
|
2.9
|
20.0
|
0.0
|
O1G
|
B:GTP402
|
3.1
|
12.2
|
1.0
|
O1A
|
B:GTP402
|
3.2
|
20.8
|
1.0
|
O5'
|
B:GTP402
|
3.6
|
9.9
|
1.0
|
NE2
|
B:HIS113
|
3.7
|
3.4
|
1.0
|
HZ3
|
C:LYS136
|
3.7
|
20.0
|
0.0
|
NH2
|
B:ARG185
|
3.8
|
26.8
|
1.0
|
O2G
|
B:GTP402
|
3.8
|
17.5
|
1.0
|
HH21
|
B:ARG185
|
4.0
|
20.0
|
0.0
|
O3G
|
B:GTP402
|
4.0
|
12.7
|
1.0
|
CE1
|
B:HIS113
|
4.1
|
20.3
|
1.0
|
O2A
|
B:GTP402
|
4.1
|
38.0
|
1.0
|
HZ2
|
C:LYS136
|
4.1
|
20.0
|
0.0
|
C5'
|
B:GTP402
|
4.2
|
14.8
|
1.0
|
HH12
|
B:ARG185
|
4.4
|
20.0
|
0.0
|
NZ
|
C:LYS136
|
4.4
|
17.9
|
1.0
|
CZ
|
B:ARG185
|
4.8
|
13.4
|
1.0
|
C3'
|
B:GTP402
|
4.8
|
17.7
|
1.0
|
CD2
|
B:HIS113
|
5.0
|
12.2
|
1.0
|
|
Phosphorus binding site 6 out
of 45 in 1a9c
Go back to
Phosphorus Binding Sites List in 1a9c
Phosphorus binding site 6 out
of 45 in the Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
Mono view
Stereo pair view
|
A full contact list of Phosphorus with other atoms in the P binding
site number 6 of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:P402
b:16.1
occ:1.00
|
PA
|
B:GTP402
|
0.0
|
16.1
|
1.0
|
O2A
|
B:GTP402
|
1.5
|
38.0
|
1.0
|
O1A
|
B:GTP402
|
1.5
|
20.8
|
1.0
|
O5'
|
B:GTP402
|
1.6
|
9.9
|
1.0
|
O3A
|
B:GTP402
|
1.6
|
21.1
|
1.0
|
C5'
|
B:GTP402
|
2.7
|
14.8
|
1.0
|
PB
|
B:GTP402
|
2.9
|
24.7
|
1.0
|
O1B
|
B:GTP402
|
3.2
|
34.1
|
1.0
|
HZ3
|
C:LYS136
|
3.3
|
20.0
|
0.0
|
O3B
|
B:GTP402
|
3.5
|
26.1
|
1.0
|
CG2
|
C:THR87
|
3.7
|
24.1
|
1.0
|
C4'
|
B:GTP402
|
3.8
|
14.3
|
1.0
|
OG1
|
C:THR87
|
3.9
|
26.7
|
1.0
|
O2B
|
B:GTP402
|
4.1
|
32.7
|
1.0
|
C3'
|
B:GTP402
|
4.2
|
17.7
|
1.0
|
NZ
|
C:LYS136
|
4.2
|
17.9
|
1.0
|
CB
|
C:THR87
|
4.4
|
15.7
|
1.0
|
CE
|
C:LYS136
|
4.5
|
2.0
|
1.0
|
HZ2
|
C:LYS136
|
4.5
|
20.0
|
0.0
|
HG1
|
C:THR87
|
4.7
|
20.0
|
0.0
|
HE2
|
B:HIS113
|
4.8
|
20.0
|
0.0
|
HD1
|
B:HIS112
|
4.9
|
20.0
|
0.0
|
O3'
|
B:GTP402
|
4.9
|
32.2
|
1.0
|
PG
|
B:GTP402
|
4.9
|
16.7
|
1.0
|
HZ1
|
C:LYS136
|
5.0
|
20.0
|
0.0
|
|
Phosphorus binding site 7 out
of 45 in 1a9c
Go back to
Phosphorus Binding Sites List in 1a9c
Phosphorus binding site 7 out
of 45 in the Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
Mono view
Stereo pair view
|
A full contact list of Phosphorus with other atoms in the P binding
site number 7 of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:P403
b:15.9
occ:1.00
|
PG
|
C:GTP403
|
0.0
|
15.9
|
1.0
|
O2G
|
C:GTP403
|
1.5
|
13.9
|
1.0
|
O1G
|
C:GTP403
|
1.5
|
3.4
|
1.0
|
O3G
|
C:GTP403
|
1.6
|
26.2
|
1.0
|
O3B
|
C:GTP403
|
1.6
|
21.6
|
1.0
|
HH11
|
D:ARG139
|
2.6
|
20.0
|
0.0
|
HH12
|
C:ARG185
|
2.7
|
20.0
|
0.0
|
PB
|
C:GTP403
|
2.9
|
23.5
|
1.0
|
HH12
|
D:ARG139
|
2.9
|
20.0
|
0.0
|
HH22
|
C:ARG185
|
3.0
|
20.0
|
0.0
|
HZ2
|
D:LYS136
|
3.0
|
20.0
|
0.0
|
O1B
|
C:GTP403
|
3.1
|
36.4
|
1.0
|
NH1
|
D:ARG139
|
3.1
|
9.2
|
1.0
|
HG
|
D:SER135
|
3.3
|
20.0
|
0.0
|
O2B
|
C:GTP403
|
3.5
|
12.6
|
1.0
|
OG
|
D:SER135
|
3.5
|
25.6
|
1.0
|
NH1
|
C:ARG185
|
3.7
|
32.0
|
1.0
|
NH2
|
C:ARG185
|
3.9
|
48.4
|
1.0
|
HZ3
|
D:LYS136
|
3.9
|
20.0
|
0.0
|
NZ
|
D:LYS136
|
3.9
|
8.5
|
1.0
|
O3A
|
C:GTP403
|
4.1
|
17.9
|
1.0
|
CZ
|
C:ARG185
|
4.3
|
29.0
|
1.0
|
HH11
|
C:ARG185
|
4.4
|
20.0
|
0.0
|
CZ
|
D:ARG139
|
4.4
|
14.7
|
1.0
|
HE2
|
C:HIS113
|
4.4
|
20.0
|
0.0
|
CB
|
D:SER135
|
4.4
|
8.2
|
1.0
|
C3'
|
C:GTP403
|
4.5
|
21.3
|
1.0
|
O1A
|
C:GTP403
|
4.7
|
22.8
|
1.0
|
HH21
|
C:ARG185
|
4.7
|
20.0
|
0.0
|
HZ1
|
D:LYS136
|
4.7
|
20.0
|
0.0
|
CE
|
D:LYS136
|
4.7
|
2.0
|
1.0
|
CE1
|
C:HIS113
|
4.8
|
16.6
|
1.0
|
O3'
|
C:GTP403
|
4.8
|
23.3
|
1.0
|
O5'
|
C:GTP403
|
4.8
|
25.9
|
1.0
|
PA
|
C:GTP403
|
4.9
|
23.7
|
1.0
|
NE2
|
C:HIS113
|
4.9
|
24.9
|
1.0
|
CD
|
D:ARG139
|
4.9
|
5.3
|
1.0
|
H
|
C:ILE187
|
4.9
|
20.0
|
0.0
|
|
Phosphorus binding site 8 out
of 45 in 1a9c
Go back to
Phosphorus Binding Sites List in 1a9c
Phosphorus binding site 8 out
of 45 in the Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
Mono view
Stereo pair view
|
A full contact list of Phosphorus with other atoms in the P binding
site number 8 of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:P403
b:23.5
occ:1.00
|
PB
|
C:GTP403
|
0.0
|
23.5
|
1.0
|
O1B
|
C:GTP403
|
1.5
|
36.4
|
1.0
|
O2B
|
C:GTP403
|
1.5
|
12.6
|
1.0
|
O3A
|
C:GTP403
|
1.6
|
17.9
|
1.0
|
O3B
|
C:GTP403
|
1.6
|
21.6
|
1.0
|
PG
|
C:GTP403
|
2.9
|
15.9
|
1.0
|
HE2
|
C:HIS113
|
2.9
|
20.0
|
0.0
|
PA
|
C:GTP403
|
2.9
|
23.7
|
1.0
|
HH22
|
C:ARG185
|
2.9
|
20.0
|
0.0
|
O1G
|
C:GTP403
|
3.1
|
3.4
|
1.0
|
O1A
|
C:GTP403
|
3.2
|
22.8
|
1.0
|
O5'
|
C:GTP403
|
3.6
|
25.9
|
1.0
|
NE2
|
C:HIS113
|
3.7
|
24.9
|
1.0
|
NH2
|
C:ARG185
|
3.7
|
48.4
|
1.0
|
O2G
|
C:GTP403
|
3.8
|
13.9
|
1.0
|
HZ3
|
D:LYS136
|
3.8
|
20.0
|
0.0
|
HH21
|
C:ARG185
|
3.9
|
20.0
|
0.0
|
O3G
|
C:GTP403
|
4.0
|
26.2
|
1.0
|
CE1
|
C:HIS113
|
4.1
|
16.6
|
1.0
|
O2A
|
C:GTP403
|
4.1
|
39.8
|
1.0
|
HZ2
|
D:LYS136
|
4.2
|
20.0
|
0.0
|
C5'
|
C:GTP403
|
4.3
|
21.9
|
1.0
|
HH12
|
C:ARG185
|
4.4
|
20.0
|
0.0
|
NZ
|
D:LYS136
|
4.5
|
8.5
|
1.0
|
CZ
|
C:ARG185
|
4.8
|
29.0
|
1.0
|
C3'
|
C:GTP403
|
4.9
|
21.3
|
1.0
|
CD2
|
C:HIS113
|
4.9
|
24.2
|
1.0
|
|
Phosphorus binding site 9 out
of 45 in 1a9c
Go back to
Phosphorus Binding Sites List in 1a9c
Phosphorus binding site 9 out
of 45 in the Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
Mono view
Stereo pair view
|
A full contact list of Phosphorus with other atoms in the P binding
site number 9 of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:P403
b:23.7
occ:1.00
|
PA
|
C:GTP403
|
0.0
|
23.7
|
1.0
|
O2A
|
C:GTP403
|
1.5
|
39.8
|
1.0
|
O1A
|
C:GTP403
|
1.5
|
22.8
|
1.0
|
O5'
|
C:GTP403
|
1.6
|
25.9
|
1.0
|
O3A
|
C:GTP403
|
1.6
|
17.9
|
1.0
|
C5'
|
C:GTP403
|
2.7
|
21.9
|
1.0
|
PB
|
C:GTP403
|
2.9
|
23.5
|
1.0
|
HG1
|
D:THR87
|
3.0
|
20.0
|
0.0
|
O1B
|
C:GTP403
|
3.2
|
36.4
|
1.0
|
HZ3
|
D:LYS136
|
3.5
|
20.0
|
0.0
|
O3B
|
C:GTP403
|
3.5
|
21.6
|
1.0
|
C4'
|
C:GTP403
|
3.9
|
15.7
|
1.0
|
CG2
|
D:THR87
|
3.9
|
35.2
|
1.0
|
OG1
|
D:THR87
|
3.9
|
50.6
|
1.0
|
O2B
|
C:GTP403
|
4.1
|
12.6
|
1.0
|
C3'
|
C:GTP403
|
4.3
|
21.3
|
1.0
|
NZ
|
D:LYS136
|
4.4
|
8.5
|
1.0
|
CB
|
D:THR87
|
4.4
|
29.0
|
1.0
|
CE
|
D:LYS136
|
4.6
|
2.0
|
1.0
|
HZ2
|
D:LYS136
|
4.6
|
20.0
|
0.0
|
HE2
|
C:HIS113
|
4.7
|
20.0
|
0.0
|
HD1
|
C:HIS112
|
4.8
|
20.0
|
0.0
|
PG
|
C:GTP403
|
4.9
|
15.9
|
1.0
|
O3'
|
C:GTP403
|
4.9
|
23.3
|
1.0
|
|
Phosphorus binding site 10 out
of 45 in 1a9c
Go back to
Phosphorus Binding Sites List in 1a9c
Phosphorus binding site 10 out
of 45 in the Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp
Mono view
Stereo pair view
|
A full contact list of Phosphorus with other atoms in the P binding
site number 10 of Gtp Cyclohydrolase I (C110S Mutant) in Complex with Gtp within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:P404
b:20.4
occ:1.00
|
PG
|
D:GTP404
|
0.0
|
20.4
|
1.0
|
O2G
|
D:GTP404
|
1.5
|
28.6
|
1.0
|
O1G
|
D:GTP404
|
1.5
|
19.3
|
1.0
|
O3G
|
D:GTP404
|
1.6
|
19.7
|
1.0
|
O3B
|
D:GTP404
|
1.7
|
35.4
|
1.0
|
HG
|
E:SER135
|
2.6
|
20.0
|
0.0
|
HH11
|
E:ARG139
|
2.6
|
20.0
|
0.0
|
HH12
|
D:ARG185
|
2.7
|
20.0
|
0.0
|
PB
|
D:GTP404
|
2.9
|
34.5
|
1.0
|
HH12
|
E:ARG139
|
2.9
|
20.0
|
0.0
|
HH22
|
D:ARG185
|
2.9
|
20.0
|
0.0
|
HZ2
|
E:LYS136
|
3.1
|
20.0
|
0.0
|
O1B
|
D:GTP404
|
3.1
|
32.7
|
1.0
|
NH1
|
E:ARG139
|
3.1
|
23.6
|
1.0
|
OG
|
E:SER135
|
3.5
|
32.7
|
1.0
|
O2B
|
D:GTP404
|
3.5
|
22.7
|
1.0
|
NH1
|
D:ARG185
|
3.6
|
38.0
|
1.0
|
NH2
|
D:ARG185
|
3.8
|
38.9
|
1.0
|
HZ3
|
E:LYS136
|
3.9
|
20.0
|
0.0
|
NZ
|
E:LYS136
|
3.9
|
22.2
|
1.0
|
O3A
|
D:GTP404
|
4.1
|
29.4
|
1.0
|
CZ
|
D:ARG185
|
4.2
|
22.7
|
1.0
|
HH11
|
D:ARG185
|
4.3
|
20.0
|
0.0
|
HE2
|
D:HIS113
|
4.4
|
20.0
|
0.0
|
CZ
|
E:ARG139
|
4.4
|
28.7
|
1.0
|
CB
|
E:SER135
|
4.4
|
26.2
|
1.0
|
C3'
|
D:GTP404
|
4.5
|
37.2
|
1.0
|
HH21
|
D:ARG185
|
4.6
|
20.0
|
0.0
|
O1A
|
D:GTP404
|
4.7
|
24.4
|
1.0
|
HZ1
|
E:LYS136
|
4.7
|
20.0
|
0.0
|
CE
|
E:LYS136
|
4.7
|
13.3
|
1.0
|
CE1
|
D:HIS113
|
4.8
|
16.6
|
1.0
|
O3'
|
D:GTP404
|
4.8
|
31.2
|
1.0
|
O5'
|
D:GTP404
|
4.8
|
23.5
|
1.0
|
H
|
D:ILE187
|
4.9
|
20.0
|
0.0
|
NE2
|
D:HIS113
|
4.9
|
27.4
|
1.0
|
PA
|
D:GTP404
|
4.9
|
33.1
|
1.0
|
CD
|
E:ARG139
|
5.0
|
14.3
|
1.0
|
|
Reference:
G.Auerbach,
A.Bracher,
H.Nar,
M.Fischer,
C.Hoesl,
R.Huber,
A.Bacher.
Gtp Cyclohydrolase I in Complex with Gtp at 2.1 A Resolution To Be Published.
Page generated: Fri Sep 25 12:32:04 2020
|