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Phosphorus in PDB 1a72: An Active-Site Double Mutant (PHE93->Trp, VAL203->Ala) of Horse Liver Alcohol Dehydrogenase in Complex with the Isosteric Nad Analog CpadEnzymatic activity of An Active-Site Double Mutant (PHE93->Trp, VAL203->Ala) of Horse Liver Alcohol Dehydrogenase in Complex with the Isosteric Nad Analog Cpad
All present enzymatic activity of An Active-Site Double Mutant (PHE93->Trp, VAL203->Ala) of Horse Liver Alcohol Dehydrogenase in Complex with the Isosteric Nad Analog Cpad:
1.1.1.1; Protein crystallography data
The structure of An Active-Site Double Mutant (PHE93->Trp, VAL203->Ala) of Horse Liver Alcohol Dehydrogenase in Complex with the Isosteric Nad Analog Cpad, PDB code: 1a72
was solved by
T.D.Colby,
B.J.Bahnson,
J.K.Chin,
J.P.Klinman,
B.M.Goldstein,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Phosphorus Binding Sites:
The binding sites of Phosphorus atom in the An Active-Site Double Mutant (PHE93->Trp, VAL203->Ala) of Horse Liver Alcohol Dehydrogenase in Complex with the Isosteric Nad Analog Cpad
(pdb code 1a72). This binding sites where shown within
5.0 Angstroms radius around Phosphorus atom.
In total 2 binding sites of Phosphorus where determined in the An Active-Site Double Mutant (PHE93->Trp, VAL203->Ala) of Horse Liver Alcohol Dehydrogenase in Complex with the Isosteric Nad Analog Cpad, PDB code: 1a72: Jump to Phosphorus binding site number: 1; 2; Phosphorus binding site 1 out of 2 in 1a72Go back to Phosphorus Binding Sites List in 1a72
Phosphorus binding site 1 out
of 2 in the An Active-Site Double Mutant (PHE93->Trp, VAL203->Ala) of Horse Liver Alcohol Dehydrogenase in Complex with the Isosteric Nad Analog Cpad
Mono view Stereo pair view
Phosphorus binding site 2 out of 2 in 1a72Go back to Phosphorus Binding Sites List in 1a72
Phosphorus binding site 2 out
of 2 in the An Active-Site Double Mutant (PHE93->Trp, VAL203->Ala) of Horse Liver Alcohol Dehydrogenase in Complex with the Isosteric Nad Analog Cpad
Mono view Stereo pair view
Reference:
T.D.Colby,
B.J.Bahnson,
J.K.Chin,
J.P.Klinman,
B.M.Goldstein.
Active Site Modifications in A Double Mutant of Liver Alcohol Dehydrogenase: Structural Studies of Two Enzyme-Ligand Complexes. Biochemistry V. 37 9295 1998.
Page generated: Fri Sep 25 12:21:56 2020
ISSN: ISSN 0006-2960 PubMed: 9649310 DOI: 10.1021/BI973184B |
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