Phosphorus in PDB 11bg: A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease

All present enzymatic activity of A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease:
3.1.27.5;

The structure of A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease, PDB code: 11bg was solved by L.Vitagliano, S.Adinolfi, F.Sica, A.Merlino, A.Zagari, L.Mazzarella, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	12.00 / 1.90
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.400, 66.700, 107.700, 90.00, 90.00, 90.00
R / Rfree (%)	18.9 / n/a

The binding sites of Phosphorus atom in the A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease (pdb code 11bg). This binding sites where shown within 5.0 Angstroms radius around Phosphorus atom.
In total 3 binding sites of Phosphorus where determined in the A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease, PDB code: 11bg:
Jump to Phosphorus binding site number: 1; 2; 3;

Phosphorus binding site 1 out of 3 in the A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 1 of A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease within 5.0Å range: probe atom residue distance (Å) B Occ A:P130 b:53.4 occ:1.00 P A:U2G130 0.0 53.4 1.0 O1P A:U2G130 1.5 52.5 1.0 O2P A:U2G130 1.5 53.3 1.0 O5B A:U2G130 1.6 49.7 1.0 O2D A:U2G130 1.6 56.4 1.0 C2D A:U2G130 2.6 60.4 1.0 C5B A:U2G130 2.7 44.2 1.0 OG A:SER123 3.4 22.4 1.0 C3B A:U2G130 3.4 37.9 1.0 C4B A:U2G130 3.6 39.4 1.0 C3D A:U2G130 3.6 61.8 1.0 O3D A:U2G130 3.7 61.5 1.0 O A:HOH295 3.7 23.0 1.0 N A:SER123 3.8 21.7 1.0 C1D A:U2G130 3.9 61.4 1.0 O3B A:U2G130 3.9 39.1 1.0 O A:SER123 4.0 22.5 1.0 O4B A:U2G130 4.2 35.8 1.0 C8G A:U2G130 4.3 23.6 1.0 N1U A:U2G130 4.4 61.4 1.0 CB A:SER123 4.5 21.2 1.0 CA A:ALA122 4.5 19.8 1.0 CA A:SER123 4.6 21.8 1.0 C A:ALA122 4.6 19.0 1.0 CB A:ALA122 4.7 18.7 1.0 C2B A:U2G130 4.7 36.4 1.0 C A:SER123 4.7 22.4 1.0 C1B A:U2G130 4.8 32.9 1.0 OD2 A:ASP83 4.9 21.0 1.0 C4D A:U2G130 4.9 62.9 1.0 N9G A:U2G130 4.9 26.7 1.0 NZ A:LYS104 5.0 34.0 1.0 O4D A:U2G130 5.0 63.2 1.0

Phosphorus binding site 2 out of 3 in the A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 2 of A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease within 5.0Å range: probe atom residue distance (Å) B Occ A:P131 b:30.6 occ:0.62 P A:U2G131 0.0 30.6 0.6 O2P A:U2G131 1.5 30.9 0.6 O1P A:U2G131 1.5 31.4 0.6 O5B A:U2G131 1.6 30.1 0.6 O2D A:U2G131 1.6 31.0 0.6 C2D A:U2G131 2.6 32.1 0.6 C5B A:U2G131 2.6 29.2 0.6 C1D A:U2G131 3.7 32.0 0.6 C3D A:U2G131 3.8 33.0 0.6 C4B A:U2G131 3.9 28.3 0.6 O3D A:U2G131 4.0 33.3 0.6 N1U A:U2G131 4.1 32.7 0.6 O4B A:U2G131 4.1 26.8 0.6 C2U A:U2G131 4.5 32.6 0.6 O A:HOH318 4.6 33.2 1.0 O2U A:U2G131 4.6 32.2 0.6 C6U A:U2G131 4.6 32.9 0.6 O4D A:U2G131 4.9 32.7 0.6 C4D A:U2G131 5.0 33.3 0.6 C3B A:U2G131 5.0 28.4 0.6

Phosphorus binding site 3 out of 3 in the A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease


Mono view


Stereo pair view

A full contact list of Phosphorus with other atoms in the P binding site number 3 of A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease within 5.0Å range: probe atom residue distance (Å) B Occ B:P133 b:73.7 occ:1.00 P B:U2G133 0.0 73.7 1.0 O1P B:U2G133 1.5 73.5 1.0 O2P B:U2G133 1.5 73.7 1.0 O5B B:U2G133 1.6 70.0 1.0 O2D B:U2G133 1.6 74.0 1.0 C5B B:U2G133 2.7 63.0 1.0 OG B:SER123 3.4 23.4 1.0 C3B B:U2G133 3.6 55.7 1.0 C4B B:U2G133 3.6 57.4 1.0 N B:SER123 3.7 21.0 1.0 C8G B:U2G133 3.7 41.4 1.0 O B:HOH324 4.0 47.0 1.0 O B:HOH310 4.0 43.4 1.0 O B:SER123 4.0 22.4 1.0 O3B B:U2G133 4.1 56.1 1.0 O4B B:U2G133 4.3 53.6 1.0 CB B:SER123 4.4 21.0 1.0 NH1 B:ARG85 4.4 44.3 1.0 CA B:ALA122 4.5 19.5 1.0 OD2 B:ASP83 4.5 28.5 1.0 CA B:SER123 4.5 21.2 1.0 N9G B:U2G133 4.6 43.3 1.0 N7G B:U2G133 4.6 38.7 1.0 C B:ALA122 4.6 20.0 1.0 CB B:ALA122 4.6 18.5 1.0 C B:SER123 4.7 22.5 1.0 C1B B:U2G133 4.8 50.0 1.0 C2B B:U2G133 4.8 54.2 1.0

L.Vitagliano, S.Adinolfi, F.Sica, A.Merlino, A.Zagari, L.Mazzarella. A Potential Allosteric Subsite Generated By Domain Swapping in Bovine Seminal Ribonuclease. J.Mol.Biol. V. 293 569 1999.
ISSN: ISSN 0022-2836
PubMed: 10543951
DOI: 10.1006/JMBI.1999.3158